Nicorette White Ice and Zantac (Ranitidine Injection)
Determining the interaction of Nicorette White Ice and Zantac (Ranitidine Injection) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may reduce the clearance of nicotine. Cimetidine, 600 mg given twice a day for two days, reduced clearance of an intravenous nicotine dose by 30%. Ranitidine, 300 mg given twice a day for two days, reduced clearance by 10%. The clinical significance of this interaction is not known. Patients should be monitored for increased nicotine effects when using the patches or gum for smoking cessation and dosage adjustments should be made as appropriate.
- Bendayan R, Sullivan JT, Shaw C, Frecker RC, Sellers EM "Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans." Eur J Clin Pharmacol 38 (1990): 165-9
Generic Name: nicotine
Brand name: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Commit, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ, Nicotrol Inhaler, Nicotrol NS
Synonyms: Nicorette Gum and Lozenges, Nicorette
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Zantac
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nicorette White Ice-Zantac (Ranitidine Syrup)
- Nicorette White Ice-Zantac (Ranitidine Tablets and Capsules)
- Nicorette White Ice-Zantac Cool Mint
- Nicorette White Ice-Zantac Injection
- Nicorette White Ice-Zapzyt Cleansing Topical
- Nicorette White Ice-Zapzyt Topical
- Zantac (Ranitidine Injection)-Nicotine
- Zantac (Ranitidine Injection)-Nicotine Gum
- Zantac (Ranitidine Injection)-Nicotine Gum and Lozenges
- Zantac (Ranitidine Injection)-Nicotine Inhalation, oral/nebulization
- Zantac (Ranitidine Injection)-Nicotine Inhaler
- Zantac (Ranitidine Injection)-Nicotine Lozenges