Nicotine and Otrexup injection

• Generic Name: nicotine
• Dosage Forms: n.a.
• Other Brand Names: Commit, Nicoderm CQ, Nicorette, Nicotrol Inhaler, Nicotrol NS, Leader Nicotine Polacrilex, Nicorelief, Thrive, Habitrol, Nicoderm C-Q, Nicotine System Kit

Used for nicotine replacement therapy as a temporary adjunct in the cessation of cigarette smoking either unsupervised (self-medication) or in conjunction with a behavior modification program under clinician supervision.

Nicotine replacement therapy considered one of several first-line therapies by USPHS for treatment of tobacco dependence.

Nicotine replacement therapy provides alternative sources of nicotine that help reduce the withdrawal symptoms associated with nicotine dependence. Chewing the resin complex-containing gum may act as a substitute oral activity in behavior modification.

Electronic nicotine delivery systems (ENDS) such as electronic cigarettes (e-cigarettes) have been used to aid smoking cessation attempts; however, these products are not approved by FDA for this use and evidence is limited regarding their efficacy and safety. The role of ENDS relative to conventional nicotine replacement therapies for smoking cessation remains to be established.

Ulcerative Colitis

Transdermal nicotine has been used in the management of ulcerative colitis.

• Generic Name: methotrexate
• Dosage Forms: injection, solution
• Other Brand Names: Methotrexate Sodium, Preservative Free, Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep

Otrexup interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Otrexup is used to treat leukemia and certain types of cancer of the breast, skin, head and neck, or lung. This medicine is also used to treat severe psoriasis and rheumatoid arthritis.

Otrexup is usually given after other treatments have failed.

Otrexup may also be used for purposes not listed in this medication guide.