Nicotrol NS and Sunmark Acid Reducer
Determining the interaction of Nicotrol NS and Sunmark Acid Reducer and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may reduce the clearance of nicotine. Cimetidine, 600 mg given twice a day for two days, reduced clearance of an intravenous nicotine dose by 30%. Ranitidine, 300 mg given twice a day for two days, reduced clearance by 10%. The clinical significance of this interaction is not known. Patients should be monitored for increased nicotine effects when using the patches or gum for smoking cessation and dosage adjustments should be made as appropriate.
- Bendayan R, Sullivan JT, Shaw C, Frecker RC, Sellers EM "Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans." Eur J Clin Pharmacol 38 (1990): 165-9
Generic Name: nicotine
Brand name: Nicotrol Inhaler, Nicotrol NS, Commit, Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ
Synonyms: Nicotrol NS (nasal, inhalation)
Generic Name: famotidine
Brand name: Pepcid, Heartburn Relief, Pepcid AC, Pepcid AC Maximum Strength, Pepcid AC Chewable Tablets, Pepcid Oral Suspension
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nicotrol NS-Sunmark Acid Reducer Maximum Strength
- Nicotrol NS-Sunmark Acid Reducer Ranitidine
- Nicotrol NS-Sunmark All Day Allergy-D
- Nicotrol NS-Sunmark Anti-Diarrheal
- Nicotrol NS-Sunmark Anti-Diarrheal Tablet
- Nicotrol NS-SunMark ClearLax
- Sunmark Acid Reducer-Nicotrol NS nasal, inhalation
- Sunmark Acid Reducer-Nicotrol Oral, Transdermal
- Sunmark Acid Reducer-Nidagel
- Sunmark Acid Reducer-Nifediac CC
- Sunmark Acid Reducer-Nifedical XL
- Sunmark Acid Reducer-Nifedipine