Nicotrol Oral, Transdermal and Nizatidine
Determining the interaction of Nicotrol Oral, Transdermal and Nizatidine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may reduce the clearance of nicotine. Cimetidine, 600 mg given twice a day for two days, reduced clearance of an intravenous nicotine dose by 30%. Ranitidine, 300 mg given twice a day for two days, reduced clearance by 10%. The clinical significance of this interaction is not known. Patients should be monitored for increased nicotine effects when using the patches or gum for smoking cessation and dosage adjustments should be made as appropriate.
- Bendayan R, Sullivan JT, Shaw C, Frecker RC, Sellers EM "Effect of cimetidine and ranitidine on the hepatic and renal elimination of nicotine in humans." Eur J Clin Pharmacol 38 (1990): 165-9
Generic Name: nicotine
Brand name: Nicotrol Inhaler, Nicotrol NS, Commit, Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive, Habitrol, Nicoderm C-Q, Nicotine System Kit, Nicoderm CQ
Synonyms: Nicotrol Inhaler (nasal, inhalation), Nicotrol Inhalant
Generic Name: nizatidine
Brand name: Axid, Axid AR, Axid Pulvules
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nicotrol Oral, Transdermal-Nizatidine Capsules and Tablets
- Nicotrol Oral, Transdermal-Nizatidine Oral Solution
- Nicotrol Oral, Transdermal-Nizatidine Solution
- Nicotrol Oral, Transdermal-Nizoral
- Nicotrol Oral, Transdermal-No Doz Maximum Strength
- Nicotrol Oral, Transdermal-Nocdurna
- Nizatidine-Nidagel
- Nizatidine-Nifediac CC
- Nizatidine-Nifedical XL
- Nizatidine-Nifedipine
- Nizatidine-Nifedipine Capsules
- Nizatidine-Nifedipine Extended-Release Tablets