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Nifedical XL and Suprax Tablets

Determining the interaction of Nifedical XL and Suprax Tablets and the possibility of their joint administration.

Check result:
Nifedical XL <> Suprax Tablets
Relevance: 06.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Nifedipine may increase the bioavailability of cefixime. The mechanism appears to be nifedipine enhancement of cefixime absorption. This interaction appears to be clinically insignificant.

References
  • Duverne C, Bouten A, Deslandes A "Modification of cefixime bioavailabity by nifedipine in humans: involvement of the dipeptide carrier system." Antimicrob Agents Chemother 36 (1992): 2462-7
Nifedical XL

Generic Name: nifedipine

Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat

Synonyms: Nifedical XL (Oral)

Suprax Tablets

Generic Name: cefixime

Brand name: Suprax

Synonyms: Suprax

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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