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Nifedical XL and Ulipristal Tablets (Ella)

Determining the interaction of Nifedical XL and Ulipristal Tablets (Ella) and the possibility of their joint administration.

Check result:
Nifedical XL <> Ulipristal Tablets (Ella)
Relevance: 06.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration with CYP450 3A4 inhibitors may increase the plasma concentrations of ulipristal, which is primarily metabolized by the isoenzyme. The clinical relevance is unknown.

References
  • "Product Information. ella (ulipristal)." Afaxys Inc., Charleston, SC.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Nifedical XL

Generic Name: nifedipine

Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat

Synonyms: Nifedical XL (Oral)

Ulipristal Tablets (Ella)

Generic Name: ulipristal

Brand name: Ella, Ella

Synonyms: Ulipristal

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle