Nifedipine and Omeprazole and sodium bicarbonate
Determining the interaction of Nifedipine and Omeprazole and sodium bicarbonate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Omeprazole may increase the absorption or interfere with the metabolism of at least one dihydropyridine calcium channel blocker (CCB)--nifedipine. The pharmacologic effect of nifedipine may be enhanced. Although unlikely to be of clinical significance, when omeprazole and a CCB are coadministered, monitoring for CCB toxicity should be considered.
- Andersson T "Omeprazole drug interaction studies." Clin Pharmacokinet 21 (1991): 195-212
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Adalat (nifedipine)." Bayer, West Haven, CT.
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: NIFEdipine
Generic Name: omeprazole / sodium bicarbonate
Brand name: Zegerid, Zegerid OTC
Synonyms: Omeprazole and Sodium Bicarbonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Nifedipine-Omeprazole and Sodium Bicarbonate Capsule
- Nifedipine-Omeprazole and Sodium Bicarbonate Capsules
- Nifedipine-Omeprazole and Sodium Bicarbonate Powder Packets
- Nifedipine-Omeprazole Delayed-Release Capsules
- Nifedipine-Omeprazole Delayed-Release Capsules and Tablets (OTC)
- Nifedipine-Omeprazole Orally-Disintegrating Tablets
- Omeprazole and sodium bicarbonate-Nifedipine Capsules
- Omeprazole and sodium bicarbonate-Nifedipine Extended-Release Tablets
- Omeprazole and sodium bicarbonate-Niferex
- Omeprazole and sodium bicarbonate-Niferex Elixir
- Omeprazole and sodium bicarbonate-Night Cast R Topical
- Omeprazole and sodium bicarbonate-Night Cast S Topical