Nikita and Warfarin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

According to the product labeling, pitavastatin 4 mg daily had no significant effect on the pharmacokinetics of R(+) and S(-) warfarin or the steady-state pharmacodynamics of warfarin in healthy volunteers. Pitavastatin also did not affect prothrombin time (PT) or international normalized ratio (INR) when administered to patients receiving chronic warfarin treatment. However, PT or INR should be monitored when pitavastatin is added to warfarin therapy. The same precaution may also be applicable to other oral anticoagulants.

Nikita

Generic Name: pitavastatin

Brand name: Livalo, Zypitamag

Synonyms: Nikita (Oral)

What is Nikita?

Warfarin

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Warfarin?