Nintedanib Esylate and Promethazine

• Generic Name: nintedanib
• Dosage Forms: n.a.
• Other Brand Names: Ofev

Treatment of idiopathic pulmonary fibrosis (IPF) (designated an orphan drug by FDA for this use).

• Generic Name: promethazine
• Dosage Forms: n.a.
• Other Brand Names: Phenergan, Phenadoz, Promethegan

Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.

Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections.