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Nipent and Zyloprim

Determining the interaction of Nipent and Zyloprim and the possibility of their joint administration.

Check result:

Nipent <> Zyloprim

Relevance: 04.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Pentostatin may increase the risk of a hypersensitivity reaction to allopurinol. The mechanism is unknown.

References

Steinmetz JC, DeConti R, Ginsburg R "Hypersensitivity vasculitis associated with 2-deoxycoformycin and allopurinol therapy." Am J Med 86 (1989): 498-9

Nipent

Generic Name: pentostatin

Brand name: Nipent

Synonyms: n.a.

What is Nipent?

Zyloprim

Generic Name: allopurinol

Brand name: Zyloprim, Lopurin, Aloprim

Synonyms: n.a.

What is Zyloprim?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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