Niraparib Tosylate and Rasagiline Mesylate

• Generic Name: niraparib
• Dosage Forms: n.a.
• Other Brand Names: Zejula

Maintenance therapy of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients in complete or partial response following platinum-based chemotherapy (designated an orphan drug by FDA for this use).

In the principal efficacy study (NOVA), niraparib maintenance therapy substantially prolonged progression-free survival in patients with platinum-sensitive epithelial ovarian, fallopian tube, or primary peritoneal cancer compared with placebo regardless of the presence or absence of germline BRCA mutations or homologous recombination deficiency (HRD) status.

• Generic Name: rasagiline
• Dosage Forms: n.a.
• Other Brand Names: Azilect

Symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]).

May be used as monotherapy or as adjunctive therapy to levodopa or other antiparkinsonian agents (e.g., dopamine agonists).