Norethindrone and Mestranol and Zolmitriptan nasal
Determining the interaction of Norethindrone and Mestranol and Zolmitriptan nasal and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Retrospective pharmacokinetic analysis indicate that plasma concentrations of zolmitriptan may be higher in females taking concurrent oral contraceptives. Mean Cmax and AUC of zolmitriptan were 30% and 50% higher, respectively, and Tmax was delayed by one-half hour in females taking oral contraceptives. The mechanism and clinical significance are unknown. The effect of zolmitriptan on the pharmacokinetics of oral contraceptives has not been reported. Patients should be advised to notify their physician promptly if they experience sedation, dizziness, paresthesia, chest pain or tightness, shortness of breath, or irregular heartbeats.
- "Product Information. Zomig (zolmitriptan)." Zeneca Pharmaceuticals, Wilmington, DE.
Generic Name: mestranol / norethindrone
Brand name: Necon 1/50, Norinyl 1+50
Synonyms: n.a.
Generic Name: zolmitriptan
Brand name: Zomig, Zomig-ZMT
Synonyms: Zolmitriptan, ZOLMitriptan
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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