Norgesic Forte and Varicella Virus Vaccine
Determining the interaction of Norgesic Forte and Varicella Virus Vaccine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using aspirin together with varicella virus vaccine. Using these medications together may be associated with Reye's syndrome. Reye's syndrome is a sudden, sometimes fatal, disease of the brain with degeneration of the liver and occurs in children (most cases 4-12 years of age). If you are receiving varicella virus vaccine and less than 18 years of age you should avoid the use of aspirin for six weeks after immunization with varicella virus vaccine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: In pediatric patients, use of varicella virus vaccine during salicylate or salicylate-containing therapy may pose a theoretical risk of Reye's syndrome based on known association of the syndrome with salicylates and natural varicella infection. Children and adolescents receiving the vaccine in U.S. clinical studies were instructed not to use salicylates for six weeks after vaccination. There were no reports of Reye's syndrome during these studies.
MANAGEMENT: Vaccine recipients less than 18 years of age should avoid the use of salicylates for six weeks after immunization with varicella virus vaccine.
- "Product Information. Varivax (varicella virus vaccine live)." Merck & Co, Inc, West Point, PA.
- "Product Information. Dipentum (olsalazine)." Meda Pharmaceuticals, Somerset, NJ.
Generic Name: aspirin / caffeine / orphenadrine
Brand name: Norgesic Forte, Orphengesic Forte, Norgesic, Orphengesic
Synonyms: n.a.
Generic Name: varicella virus vaccine
Brand name: Varivax
Synonyms: Varicella virus (chickenpox) vaccine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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