Norpramin and Tolcapone
Determining the interaction of Norpramin and Tolcapone and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using desipramine together with tolcapone may lead to increased side effects. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: An increased incidence of adverse effects may occur when tolcapone is given together with levodopa/carbidopa and desipramine. The mechanism of the interaction is unknown.
MANAGEMENT: The manufacturer recommends caution if desipramine is given to patients receiving tolcapone and levodopa/carbidopa.
- "Product Information. Tasmar (tolcapone)." Valeant Pharmaceuticals, Costa Mesa, CA.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.