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NovoLog and Potassium chloride and sodium chloride

Determining the interaction of NovoLog and Potassium chloride and sodium chloride and the possibility of their joint administration.

Check result:

NovoLog <> Potassium chloride and sodium chloride

Relevance: 19.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Limited data suggest that potassium repletion may partially or completely reverse glucose intolerance in some patients with liver cirrhosis. The effect of insulin may be potentiated, and the risk of hypoglycemia increased. The mechanism by which potassium improves glucose tolerance has not been established, but it apparently does not involve a further increase in the already excessive insulin secretion associated with cirrhosis. The implications for glucose intolerance in patients without liver cirrhosis are not known.

References

Hiatt N, Davidson MB, Bonorris G "The effect of potassium chloride infusion on insulin secretion in vivo." Horm Metab Res 4 (1972): 64-8
Conn HO "Cirrhosis and diabetes. IV. Effect of potassium chloride administration on glucose and insulin metabolism." Am J Med Sci 259 (1970): 394-404
DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ "The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man." J Clin Invest 55 (1975): 845-55

NovoLog

Generic Name: insulin aspart

Brand name: NovoLog, NovoLog FlexPen, NovoLog PenFill, Fiasp, NovoLOG FlexTouch, Fiasp PenFill, Fiasp FlexTouch

Synonyms: Novolog

What is NovoLog?

Potassium chloride and sodium chloride

Generic Name: potassium chloride / sodium chloride

Brand name: Buffered Salt, Thermotabs

Synonyms: Potassium Chloride in Sodium Chloride

What is Potassium chloride and sodium chloride?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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