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NRS Nasal and Spravato

Determining the interaction of NRS Nasal and Spravato and the possibility of their joint administration.

Check result:

NRS Nasal <> Spravato

Relevance: 23.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

It is not known how esketamine and oxymetazoline nasal may affect each other when they are used at the same time. If you need to use oxymetazoline nasal on a day when dosing of esketamine is scheduled, you should use it at least one hour before esketamine. Talk to your doctor or pharmacist if you have questions on how to take these or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Data are limited with respect to any potential interaction between intranasal esketamine and other nasal products during concomitant administration. In pharmacokinetic studies, mometasone furoate and oxymetazoline hydrochloride administered intranasally one hour before esketamine demonstrated no clinically significant effects on esketamine peak plasma concentration and exposure.

MANAGEMENT: To minimize the risk of interaction, patients who require a nasal corticosteroid or nasal decongestant on a day when esketamine dosing is scheduled should administer these medications at least one hour before esketamine.

References

"Product Information. Spravato (esketamine)." Janssen Pharmaceuticals, Titusville, NJ.

NRS Nasal

Generic Name: oxymetazoline nasal

Brand name: 12 Hour Nasal, Afrin, Afrin No Drip Sinus, Allerest 12 Hour Nasal Spray, Dristan 12-Hour, Duramist Plus, Duration, Mucinex Full Force, Mucinex Moisture Smart, Nasal Mist, Neo-Synephrine 12 Hour, Nostrilla, NRS Nasal, Sinarest Nasal, Sinex Long-Acting, Sudafed OM Sinus Cold, Zicam Extreme Congestion Relief, Zicam Sinus Relief, 12 Hour Decongestant, 12 Hour Nasal Decongestant, 12 Hour Nasal Relief Spray, 12 Hour Nasal Spray, Afrin 12 Hour, NTZ Long Acting Nasal, Genasal, Oxymeta-12, Twice-A-Day, Oxyfrin, Afrin Nasal Sinus, Four-Way Nasal Spray, Neo-Synephrine 12 Hour Extra Moisturizing, Afrin No Drip Severe Congestion, Afrin Pump Mist, Afrin Extra Moisturizing, Afrin Severe Congestion, Afrin Severe Congestion NoDrip, Afrin NoDrip Extra Moisturizing, Afrin All Night NoDrip, Sudafed OM Sinus Congestion, Sinex 12 Hour Moisturizing, Sinex 12 Hour, Sinex 12 Hour Ultra Fine Mist, Mucinex Sinus-Max Moisture Smart, Sinex Moisturizing Ultra Fine Mist, Sinex Severe Ultra Fine Mist, Sinex Severe

Synonyms: n.a.

What is NRS Nasal?

Spravato

Generic Name: esketamine

Brand name: Spravato

Synonyms: Spravato Nasal Spray

What is Spravato?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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