Nymalize (Nimodipine Capsules) and Phenobarbital Elixir
Determining the interaction of Nymalize (Nimodipine Capsules) and Phenobarbital Elixir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using niMODipine together with PHENobarbital is not recommended. Combining these medications may significantly decrease the blood levels of niMODipine, which can make the medication less effective or ineffective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:CONTRAINDICATED: Coadministration with potent inducers of CYP450 3A4 may significantly reduce the plasma concentrations and pharmacologic effects of oral nimodipine, which is a substrate of the isoenzyme in the intestinal mucosa and liver.
MANAGEMENT: Concomitant use of oral nimodipine with potent CYP450 3A4 inducers is considered contraindicated by some authorities.
- "Product Information. Nimotop (nimodipine)." Bayer, West Haven, CT.
- Bahls FH, Ozuna J, Ritchie DE "Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin." Neurology 41 (1991): 740-2
Generic Name: nimodipine
Brand name: Nymalize, Nimotop
Synonyms: Nymalize
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: Phenobarbital, PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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