NyQuil Severe Cold & Flu and Pegvaliase-pqpz Subcutaneous

• Generic Name: acetaminophen / dextromethorphan / doxylamine / phenylephrine
• Dosage Forms: n.a.
• Other Brand Names: Alka-Seltzer Plus Night-Time Cold, Delsym Adult Night Time Multi-Symptom, Mucinex Fast-Max Night Time Cold & Flu, NyQuil Severe Cold & Flu, Tylenol Cold Multi-Symptom Nighttime, Tylenol Warming Cold Multi-Symptom Nighttime, Tylenol Cold Plus Flu Plus Cough Night

Acetaminophen is a pain reliever and fever reducer.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

NyQuil Severe Cold & Flu is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

NyQuil Severe Cold & Flu will not treat a cough that is caused by smoking, asthma, or emphysema.

NyQuil Severe Cold & Flu may also be used for purposes not listed in this medication guide.

• Generic Name: pegvaliase
• Dosage Forms: n.a.
• Other Brand Names: Palynziq

Pegvaliase-pqpz injection is used to lower phenylalanine levels in the blood in adults with phenylketonuria (PKU), who have uncontrolled blood phenylalanine levels with their current treatment.

Pegvaliase-pqpz is available only under a restricted distribution program called Palynziq™ REMS (Risk Evaluation and Mitigation Strategy) Program.