Obinutuzumab and Rituxan

• Generic Name: obinutuzumab
• Dosage Forms: n.a.
• Other Brand Names: Gazyva

Obinutuzumab is a monoclonal antibody that affects the actions of the body's immune system. Obinutuzumab strengthens your immune system to help your body fight against tumor cells.

Obinutuzumab is used in combination with another cancer medicine called chlorambucil to treat chronic lymphocytic leukemia.

Obinutuzumab is also used in combination with other cancer medicines to treat follicular lymphoma (a type of non-Hodgkin lymphoma), or to help delay the progression of this disease.

Obinutuzumab may also be used for purposes not listed in this medication guide.

• Generic Name: rituximab
• Dosage Forms: injection, solution
• Other Brand Names: Rituxan, Truxima

Rituxan (rituximab) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. It is also used to treat other non-cancer conditions.

Rituxan is an intravenous (IV) infusion given by a healthcare professional. It is a prescription medicine used alone or in combination with other medicines to treat the following conditions:

• non-Hodgkin's lymphoma or chronic lymphocytic leukemia in adults;

• rheumatoid arthritis in adults;

• granulomatosis with polyangiitis and microscopic polyangiitis (rare disorders that cause inflammation of blood vessels and other tissues in the body) in adults and children 2 years of age and older; or

• pemphigus vulgaris (a severe autoimmune reaction that causes blisters and breakdown of the skin and mucous membranes) in adults.