Odomzo and Proferrin-ES

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with proton pump inhibitors or H2-receptor antagonists may decrease the plasma concentrations of sonidegib. The mechanism of interaction has not been described. Based on population pharmacokinetic analysis, concomitant administration of sonidegib with a proton pump inhibitor or H2-receptor antagonist decreases mean sonidegib steady-state systemic exposure (AUC) by approximately one-third. The clinical relevance of this interaction is unknown.

Odomzo

Generic Name: sonidegib

Brand name: Odomzo

Synonyms: n.a.

What is Odomzo?

Proferrin-ES

Generic Name: heme iron polypeptide

Brand name: Proferrin-ES, Baciguent, Probiotic Formula

Synonyms: n.a.

What is Proferrin-ES?