Olodaterol Hydrochloride and Trametinib

• Generic Name: olodaterol
• Dosage Forms: n.a.
• Other Brand Names: Striverdi Respimat

Olodaterol alone or in fixed combination with tiotropium used for long-term maintenance treatment of airflow obstruction associated with COPD, including chronic bronchitis and emphysema.

Not indicated for the treatment of acute bronchospasm (i.e., as rescue therapy for treatment of acute episodes of bronchospasm).

Not indicated for treatment of asthma; safety and efficacy in asthma not established.

• Generic Name: trametinib
• Dosage Forms: n.a.
• Other Brand Names: Mekinist

Trametinib is used alone or in combination with another medicine called dabrafenib (Tafinlar) to treat certain types of cancer in people who have a "BRAF" gene mutation. These medicines are for use in treating:

• melanoma (skin cancer) that cannot be treated with surgery or has spread to other parts of the body, or to prevent melanoma from coming back after surgery;

• non-small cell lung cancer that has spread to other parts of the body; or

• advanced or metastatic thyroid cancer that has spread and for which there are no other treatment options.

Trametinib may also be used for purposes not listed in this medication guide.