Omacetaxine Mepesuccinate and Ziac

• Generic Name: omacetaxine
• Dosage Forms: n.a.
• Other Brand Names: Synribo

Treatment of CML in adults in the chronic or accelerated phase of the disease after failure (secondary to resistance and/or intolerance) of prior therapy with ≥2 tyrosine kinase inhibitors (designated an orphan drug by FDA for treatment of CML ).

• Generic Name: bisoprolol / hydrochlorothiazide
• Dosage Forms: tablet, film coated
• Other Brand Names: Ziac

Ziac contains a combination of hydrochlorothiazide and bisoprolol. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Bisoprolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Ziac is used to treat high blood pressure (hypertension).

Ziac may also be used for purposes not listed in this medication guide.