Onabotulinumtoxina Intramuscular and Vivelle-Dot Transdermal

• Generic Name: onabotulinumtoxinA
• Dosage Forms: n.a.
• Other Brand Names: Botox, Botox Cosmetic

OnabotulinumtoxinA is used to treat certain eye conditions, such as blepharospasm (a condition where the eyelid will not stay open because of a muscle spasm) or strabismus (a condition where the eyes do not line up properly).

OnabotulinumtoxinA is also used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck) and some types of axillary hyperhidrosis (severe sweating of the armpits).

OnabotulinumtoxinA is used to treat increased muscle stiffness in the elbow, wrist, and finger muscles or ankle and toe muscles in adults with upper or lower limb spasticity.

OnabotulinumtoxinA is also used to prevent headaches in patients with chronic migraine (severe headaches for 15 or more days a month lasting 4 or more hours a day).

OnabotulinumtoxinA is used cosmetically to temporarily improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines), forehead lines, and crow's feet lines around the eyes (lateral canthal lines).

OnabotulinumtoxinA is also used to treat urinary incontinence (loss of bladder control) in patients with an overactive bladder caused by nervous system disorders (eg, multiple sclerosis, spinal cord injury). It is also used to treat overactive bladder with symptoms such as loss of bladder control, increased urge to urinate, and frequent need to urinate in patients who have failed treatment with other medicines.

OnabotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.

OnabotulinumtoxinA is injected into the affected muscles. Depending on your condition, more than one treatment may be required.

Onabotulinumtoxina is available only with your doctor's prescription and will be administered by your doctor.

• Generic Name: estradiol
• Dosage Forms: patch, extended release
• Other Brand Names: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot, Estraderm, Vivelle, Delestrogen, Depo-Estradiol, Divigel, Elestrin Pump, Estrasorb, EstroGel Pump, Evamist, Estrace, DepoEstradiol, Elestrin, Estradot, Estrogel, Femtrace, Femring, Gynodiol

Estradiol transdermal gel, patch, and spray are used to treat moderate to severe hot flashes and other symptoms of menopause or low amounts of estrogen. It is also used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. This medicine is also used to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally, and prevent osteoporosis after menopause.

Estradiol is an estrogen hormone. The hormone from the patch, gel, and spray is absorbed through your skin into your body. It works by preventing symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (hot flashes) in women during menopause.

This medicine is available only with your doctor's prescription.