Onasemnogene abeparvovec Zolgensma and Relistor Tablets

• Generic Name: onasemnogene abeparvovec
• Dosage Forms: n.a.
• Other Brand Names: Zolgensma, Zolgensma

Onasemnogene abeparvovec is used to treat spinal muscular atrophy in children younger than 2 years old who have a specific gene mutation that affects nerve signals to the muscles.

onasemnogene abeparvovec may not be effective in a child who is completely paralyzed or is dependent on a ventilator for breathing.

Onasemnogene abeparvovec may also be used for purposes not listed in this medication guide.

• Generic Name: methylnaltrexone
• Dosage Forms: tablet
• Other Brand Names: Relistor

Methylnaltrexone blocks the effects of opioid medication. An opioid is sometimes called a narcotic.

Methylnaltrexone reduces constipation caused by using narcotic medicine for 4 weeks or longer. Methylnaltrexone works by preventing constipation without reducing the pain-relieving effects of the narcotic.

Methylnaltrexone is given to adults who use narcotic medicine to treat severe chronic pain that is not caused by cancer. Methylnaltrexone injection is also for use in adults who have advanced illness and are receiving palliative care (treatment to relieve suffering and improve quality of life during a serious illness).

Methylnaltrexone is usually given after laxatives have been tried without successful treatment of constipation.

Methylnaltrexone may also be used for purposes not listed in this medication guide.