Orencia (Abatacept Auto-Injectors) and Simponi Aria
Determining the interaction of Orencia (Abatacept Auto-Injectors) and Simponi Aria and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using abatacept together with golimumab is not recommended. Combining these medications can increase the risk of serious infections. Contact your doctor immediately if you experience fever, chills, body aches, sore throat, muscle weakness, or other flu-like symptoms during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of abatacept in combination with a tumor necrosis factor (TNF) blocker may increase the risk of infections, possibly due to additive immunosuppressive effects. In controlled clinical trials, patients receiving concomitant abatacept and TNF antagonist therapy experienced more infections (63%) and serious infections (4.4%) than patients treated with TNF antagonists alone (43% and 0.8%, respectively). No significant enhancement of efficacy was observed with the combination relative to either agent alone.
MANAGEMENT: Concomitant use of abatacept and TNF blockers is not recommended. When transitioning from TNF antagonist therapy to abatacept therapy, patients should be monitored closely for signs of infection such as fever, chills, or sore throat.
- "Product Information. Simponi (golimumab)." Centocor Inc, Malvern, PA.
- "Product Information. Orencia (abatacept)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: abatacept
Brand name: Orencia, Orencia ClickJect, Orencia Prefilled Syringe
Synonyms: Orencia
Generic Name: golimumab
Brand name: Simponi Aria, Simponi, Simponi SmartJect
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Orencia (Abatacept Auto-Injectors)-Simuc-HD
- Orencia (Abatacept Auto-Injectors)-Simulect
- Orencia (Abatacept Auto-Injectors)-Simvastatin
- Orencia (Abatacept Auto-Injectors)-Simvastatin and niacin
- Orencia (Abatacept Auto-Injectors)-Simvastatin Oral Suspension
- Orencia (Abatacept Auto-Injectors)-Simvastatin orally disintegrating tablet
- Simponi Aria-Orencia (Abatacept Infusion)
- Simponi Aria-Orencia (Abatacept Prefilled Syringes)
- Simponi Aria-Orenitram
- Simponi Aria-Orfadin
- Simponi Aria-Orfadin (Nitisinone Capsules)
- Simponi Aria-Orfadin (Nitisinone Oral Suspension)