Orphenadrine, aspirin, and caffeine and Pertuzumab Intravenous

• Generic Name: aspirin / caffeine / orphenadrine
• Dosage Forms: tablet
• Other Brand Names: Norgesic Forte, Orphengesic Forte, Norgesic, Orphengesic

Orphenadrine and aspirin combination is used to help relax certain muscles in your body and relieve the pain and discomfort caused by strains, sprains, or other injury to your muscles. However, orphenadrine, aspirin, and caffeine does not take the place of rest, exercise, or other treatment that your doctor may recommend for your medical problem.

Orphenadrine acts in the central nervous system (CNS) to produce its muscle relaxant effects. Actions in the CNS may also be responsible for some of its side effects. Orphenadrine also has other actions (antimuscarinic) that may be responsible for some of its side effects.

This combination medicine also contains caffeine.

In the U.S., this combination medicine is available only with your doctor's prescription.

• Generic Name: pertuzumab
• Dosage Forms: n.a.
• Other Brand Names: Perjeta

Pertuzumab injection is used to treat breast cancer that has spread to other parts of the body. It is used together with other cancer medicines (eg, docetaxel, trastuzumab) to treat patients with HER2-positive breast cancer. The HER2 protein is produced by some breast tumors. Pertuzumab is a monoclonal antibody that interferes with the growth of this protein, which is eventually destroyed by the body.

Pertuzumab is also used as part of a complete treatment regimen for early breast cancer before surgery and as an additional treatment for breast cancer that is at high risk for occurring again.

Pertuzumab is to be given only by or under the immediate supervision of your doctor.