About us Contacts Drug interactions: 390 212
Drug search by name

Otrexup and Prenatal multivitamins

Determining the interaction of Otrexup and Prenatal multivitamins and the possibility of their joint administration.

Check result:
Otrexup <> Prenatal multivitamins
Relevance: 24.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Coadministration of methotrexate with vitamin preparations containing folic acid, folinic acid (leucovorin) or their derivatives may diminish the therapeutic effects of methotrexate. The proposed mechanism involves pharmacodynamic antagonism and/or competitive inhibition at the receptor site. MANAGEMENT: Although folic acid or folinic acid are frequently used along with methotrexate to reduce adverse effects or as an antidote to high dose methotrexate therapy, patients receiving methotrexate should be advised to avoid the inadvertent use of vitamin preparations containing folic acid or its derivatives. References "Product Information. Methotrexate Sodium (methotrexate)." Teva Pharmaceuticals (formerly IVAX), Miami, FL. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 Cerner Multum, Inc. "Australian Product Information." O 0

Professional:

MONITOR: Coadministration of methotrexate with vitamin preparations containing folic acid, folinic acid (leucovorin) or their derivatives may diminish the therapeutic effects of methotrexate. The proposed mechanism involves pharmacodynamic antagonism and/or competitive inhibition at the receptor site.

MANAGEMENT: Although folic acid or folinic acid are frequently used along with methotrexate to reduce adverse effects or as an antidote to high dose methotrexate therapy, patients receiving methotrexate should be advised to avoid the inadvertent use of vitamin preparations containing folic acid or its derivatives.

References
  • "Product Information. Methotrexate Sodium (methotrexate)." Teva Pharmaceuticals (formerly IVAX), Miami, FL.
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • Cerner Multum, Inc. "Australian Product Information." O 0
Otrexup

Generic Name: methotrexate

Brand name: Methotrexate Sodium, Preservative Free, Otrexup, Rasuvo, Rheumatrex Dose Pack, Trexall, Xatmep

Synonyms: Otrexup (injection)

Prenatal multivitamins

Generic Name: multivitamin, prenatal

Brand name: Vynatal FA, Zenate, CitraNatal Bloom, CitraNatal Bloom DHA, CitraNatal DHA, CitraNatal Harmony, CitraNatal Rx, Concept DHA, Concept OB, Duet DHA Balanced, Femecal OB, Folcaps Care One, Folet DHA, Folet One, Foltabs Prenatal, Foltabs Prenatal Plus DHA, Gesticare DHA, Infanate Balance, KPN Prenatal, M-Natal Plus, Mini-Prenatal, Multi-Nate 30, NeoNatal Plus, NeoNatal Vitamin, Nestabs ABC, Nexa Plus, Niva-Plus, Néevo DHA, OB Complete Gold, OB Complete One, OB Complete Petite, OB Complete Premier, One A Day Women’s Prenatal, OptiNate, Paire OB Plus DHA, PreCare, PreferaOB + DHA, PreferaOB One, PreferaOB, Prena1, Prena1 True, Prenatal 19, Prenatal One Daily, Prenatal Rx 1, Prenate AM, Prenate DHA, Prenate Essential, Prenate Mini, Prenate Pixie, Prenate Star, PreNexa Premier, Provida DHA, TriCare Prenatal, TriCare Prenatal DHA One, TriStart DHA, VIL-Rx, Vinate Care, Virt Nate, Virt-Advance, Virt-C DHA, Virt-PN DHA, Virt-PN, Virt-Vite GT, VirtPrex, Vitafol Ultra, Vitafol-Nano, Vitafol-OB+DHA, VitaPhil + DHA, Vol-Tab Rx, VP-CH-PNV, VP-Heme OB + DHA, VP-Heme OB, VP-PNV-DHA, CitraNatal DHA, PreNata, Choice-OB+DHA, Select-OB+DHA, Stuart One

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction