Ovidrel injectable and Pamidronate Disodium

• Generic Name: chorionic gonadotropin (hcg)
• Dosage Forms: injection, solution
• Other Brand Names: Novarel, Ovidrel, Pregnyl, APL, Profasi, Chorex, Gonic, Hcg, Chorigon, Choron-10

Ovidrel is a hormone that supports the normal development of an egg in a woman's ovary, and stimulates the release of the egg during ovulation.

HCG is used to cause ovulation and to treat infertility in women, and to increase sperm count in men. HCG is also used in young boys when their testicles have not dropped down into the scrotum normally. This can be caused by a pituitary gland disorder.

HCG may also be used for other purposes not listed in this medication guide.

• Generic Name: pamidronate
• Dosage Forms: n.a.
• Other Brand Names: Aredia

Used in conjunction with achievement and maintenance of adequate hydration for the treatment of moderate to severe hypercalcemia associated with malignant neoplasms, with or without bone metastases.

More conservative measures (e.g., hydration alone or combined with loop diuretics) generally used for treatment of mild or asymptomatic hypercalcemia. Corticosteroid therapy may be beneficial in hypercalcemia associated with hematological malignancies.

Consider retreatment in patients with recurrent or refractory disease.

Treatment of moderate to severe Paget’s disease of bone (osteitis deformans) in symptomatic patients with multiple bone involvement [polyostotic] and elevated concentrations of serum alkaline phosphatase and urinary hydroxyproline.

May prevent or slow progression of complications (e.g., deformities, arthritis, fractures, neurologic manifestations, spinal cord compression, heart failure) in patients with Paget’s disease of bone. May not reverse established complications (e.g., severe deformities, deafness).

Treatment in patients refractory to calcitonin or etidronate disodium.

Used as an adjunct to antineoplastic therapy for the treatment of osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma.

Decreases the incidence and delays the development of bone-related complications (e.g., fractures or spinal cord compression, bone deterioration requiring radiotherapy or orthopedic surgery), and reduces bone pain and the need for supplemental analgesic therapy.