Oxtriphylline and guaifenesin and Zovirax Oral, Intravenous
Determining the interaction of Oxtriphylline and guaifenesin and Zovirax Oral, Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited data suggest that the combination of a methyl xanthine with acyclovir may lead to elevated theophylline levels potentiating pharmacologic and adverse effects. The mechanism may be due to inhibition of theophylline oxidative metabolism. Clinical and laboratory monitoring is warranted if these agents are given concurrently. Patients receiving this combination should be advised to report any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeat to their physician.
- Maeda Y, Konishi T, Omoda K, Takeda Y, Fukuhara S, Fukuzawa M, Ohune T, Tsuya T, Tsukiai S "Inhibition of theophylline metabolism by aciclovir." Biol Pharm Bull 19 (1996): 1591-5
Generic Name: guaifenesin / oxtriphylline
Brand name:
Synonyms: Oxtriphylline and guaifenesin (Oral)
Generic Name: acyclovir
Brand name: Sitavig, Zovirax
Synonyms: Zovirax
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Oxtriphylline and guaifenesin-Zovirax Suspension
- Oxtriphylline and guaifenesin-Zovirax Topical
- Oxtriphylline and guaifenesin-ZTlido
- Oxtriphylline and guaifenesin-Zubsolv
- Oxtriphylline and guaifenesin-Zulresso
- Oxtriphylline and guaifenesin-Zumandimine
- Zovirax Oral, Intravenous-Oxy Balance Topical
- Zovirax Oral, Intravenous-Oxy Daily Wash
- Zovirax Oral, Intravenous-Oxy-10
- Zovirax Oral, Intravenous-Oxybutynin
- Zovirax Oral, Intravenous-Oxybutynin Chloride
- Zovirax Oral, Intravenous-Oxybutynin ER Tablets