Oxybutynin Chloride and Vitrakvi (Larotrectinib Capsules)

• Generic Name: oxybutynin
• Dosage Forms: n.a.
• Other Brand Names: Ditropan XL, Anturol, Gelnique, Oxytrol

Relief of symptoms of bladder instability associated with voiding (i.e., urgency, frequency, urinary leakage, urge incontinence, dysuria) in adults and pediatric patients > 5 years of age with uninhibited neurogenic or reflex neurogenic bladder (conventional tablets or oral solution).

Treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency (extended-release tablets or transdermal system).

Relief of symptoms of detrusor overactivity associated with a neurological condition (e.g., spina bifida) in pediatric patients ≥ 6 years of age (extended-release tablets).

Conventional tablets as effective as extended-release tablets.

Oxybutynin appears to be as effective as tolterodine (conventional tablets) in reducing urinary symptoms in patients with overactive bladder but is associated with a higher incidence of dry mouth.

Has been used in children for the treatment of primary nocturnal enuresis; however one study has determined that oxybutynin is not effective for management of primary nocturnal enuresis in children with a history of nocturnal enuresis and normal bladders.

• Generic Name: larotrectinib
• Dosage Forms: capsules, oral solution
• Other Brand Names: Vitrakvi

• It is used to treat cancer.