Oxycodone and acetaminophen and XaQuil XR

• Generic Name: acetaminophen / oxycodone
• Dosage Forms: n.a.
• Other Brand Names: Endocet 10/325, Endocet 25/325, Endocet 5/325, Endocet 75/325, Nalocet, Percocet 10/325, Percocet 25/325, Percocet 5/325, Percocet 75/325, Primalev, Primlev, Roxicet, Xartemis XR, Tylox, Roxilox, Endocet, Percocet 10/650, Percocet 75/500, Perloxx, Magnacet, Narvox, Xolox, Percocet

Oxycodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.

When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

Oxycodone and acetaminophen is available only with your doctor's prescription. Percocet® and Xartemis™ are available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.

• Generic Name: l-methylfolate
• Dosage Forms: n.a.
• Other Brand Names: Deplin, L-Methylfolate Formula, XaQuil XR, L-Methylfolate Formula 75

Folate is a form of B vitamin that occurs naturally in many foods. Folic acid is the man-made form of folate that is added to processed foods or vitamin and mineral supplements. Folate is needed in the human body for production of red blood cells.

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet. Folate deficiency can lead to decreased red blood cells, or anemia. Folate deficiency can also cause high levels of a certain amino acid in the blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a).

XaQuil XR is a medical food for use in people who have conditions related to folate deficiency. This medicine is also used in people with major depressive disorder who have folate deficiency, or in people with schizophrenia who have hyperhomocysteinemia related to folate deficiency.

XaQuil XR is not an antidepressant or anti-psychotic medication. However, this medicine may enhance the effects of antidepressant medications.

XaQuil XR may also be used for purposes not listed in this medication guide.