Oxycodone and Acetaminophen Extended-Release Tablets and Ranitidine Capsule
Determining the interaction of Oxycodone and Acetaminophen Extended-Release Tablets and Ranitidine Capsule and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / oxycodone
Brand name: Endocet 10/325, Endocet 25/325, Endocet 5/325, Endocet 75/325, Nalocet, Percocet 10/325, Percocet 25/325, Percocet 5/325, Percocet 75/325, Primalev, Primlev, Roxicet, Xartemis XR, Tylox, Roxilox, Endocet, Percocet 10/650, Percocet 75/500, Perloxx, Magnacet, Narvox, Xolox, Percocet
Synonyms: Acetaminophen and oxycodone, Oxycodone and Acetaminophen
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Hydrochloride
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Injection
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Suspension
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Syrup
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Tablets
- Oxycodone and Acetaminophen Extended-Release Tablets-Ranitidine Tablets and Capsules
- Ranitidine Capsule-Oxycodone and Acetaminophen Oral Solution
- Ranitidine Capsule-Oxycodone and Acetaminophen Tablets
- Ranitidine Capsule-Oxycodone and Aspirin
- Ranitidine Capsule-Oxycodone and Ibuprofen
- Ranitidine Capsule-Oxycodone and naloxone
- Ranitidine Capsule-Oxycodone and naltrexone