Oxycodone and Ibuprofen and Ranitidine Injection
Determining the interaction of Oxycodone and Ibuprofen and Ranitidine Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:H2 antagonists may alter the disposition of nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in increased or decreased plasma concentrations. Data are varied, even for the same NSAID. The mechanism may be related to inhibition of metabolism, changes in gastric pH that decrease absorption, and/or reduced urinary elimination. Statistically significant changes have been small and of limited clinical significance. Clinical monitoring of patient response and tolerance is recommended.
- Scavone JM, Greenblatt DJ, Matlis R, Harmatz JS "Interaction of oxaprozin with acetaminophen, cimetidine, and ranitidine." Eur J Clin Pharmacol 31 (1986): 371-4
- Said SA, Foda AM "Influence of cimetidine on the pharmacokinetics of piroxicam in rat and man." Arzneimittelforschung 39 (1989): 790-2
- "Product Information. Daypro (oxaprozin)." Searle, Skokie, IL.
Generic Name: ibuprofen / oxycodone
Brand name: Combunox
Synonyms: Ibuprofen and oxycodone
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Oxycodone and Ibuprofen-Ranitidine Suspension
- Oxycodone and Ibuprofen-Ranitidine Syrup
- Oxycodone and Ibuprofen-Ranitidine Tablets
- Oxycodone and Ibuprofen-Ranitidine Tablets and Capsules
- Oxycodone and Ibuprofen-Ranolazine
- Oxycodone and Ibuprofen-Ranolazine ER Tablets
- Ranitidine Injection-Oxycodone and naloxone
- Ranitidine Injection-Oxycodone and naltrexone
- Ranitidine Injection-Oxycodone Capsules
- Ranitidine Injection-Oxycodone Capsules and Tablets
- Ranitidine Injection-Oxycodone Concentrate
- Ranitidine Injection-Oxycodone ER