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Oystercal-D and Ultresa

Determining the interaction of Oystercal-D and Ultresa and the possibility of their joint administration.

Check result:

Oystercal-D <> Ultresa

Relevance: 09.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using calcium carbonate together with pancrelipase. Using these medications together may cause pancrelipase to be less effective. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Coadministration with the combination of calcium carbonate and magnesium hydroxide may reduce the therapeutic effects of pancrelipase in the treatment of steatorrhea. The mechanism involves precipitation of glycine-conjugated bile acids and formation of calcium and magnesium fatty acid soaps, resulting in a decrease in fat absorption. In addition, by increasing gastric pH, antacids may reduce the resistance of the enteric coating of some formulations of pancreatic enzymes, resulting in earlier release and destruction of enzymatic activity.

MANAGEMENT: Patients receiving pancrelipase for steatorrhea should avoid taking the medication together with a combination of calcium carbonate and magnesium hydroxide. Calcium carbonate and magnesium hydroxide may be found in certain antacids, and calcium carbonate may also be found in certain calcium or mineral supplements.

References

Lankisch PG, Creutzfeldt W "Therapy of exocrine and endocrine pancreatic insufficiency." Clin Gastroenterol 13 (1984): 985-99
"Product Information. Cotazym-S (pancrelipase)." Organon, West Orange, NJ.
"Product Information. Cotazym (pancrelipase)." Organon, West Orange, NJ.

Oystercal-D

Generic Name: calcium / vitamin d

Brand name: Calcitrate with D, Caltrate 600+D Soft Chews, Citracal + D, Os-Cal Extra D3, Oystercal-D, UpCal D, Os-Cal 250 with D, Oysco D, Dical-D, Calcet, Oyster Shell Calcium with Vitamin D, O-Cal-D, Oyster-D, Oyst-Cal-D, Caltro with Vitamin D, Oysco 500 with D, Oysco D with Calcium, Os-Cal with D, Caltrate 600 with D, Calcarb with D, Posture-D H/P, Dical Captabs, Dicalphos plus D, Os-Cal 500 with D, Caltrate 600 with D Plus Soy, Caltrate Colon Health, Calvite P & D, Sedecal D, Chewable Calcium with Vitamin D, Osteocit D Plus, Os-Cal 500 + D, Citracal Petites, Citracal Creamy Bites, Citracal 250 mg + D, Calcio Del Mar, Citrus Calcium with Vitamin D, Calcium 600+D, Risacal-D, Liquid Calcium with Vitamin D, Citracal Maximum + D, Citracal Calcium + D Slow Release 1200, Citracal Calcium Gummies, Caltrate Gummy Bites, Super Calcium 600 + D3 400, Os-Cal Calcium+D3, Caltrate 600 + D, Citracal Regular, Calcet Petites, Calcium 500+D, D3 with Calcium, Calcitrate, Caltrate 600+D, Os-Cal 500+D, Os-Cal 500+Extra D Chewable

Synonyms: n.a.

What is Oystercal-D?

Ultresa

Generic Name: pancrelipase

Brand name: Creon, Pancreaze, Pertzye, Ultresa, Viokace, Zenpep, Cotazym, Viokase, Zymase, Pancrease MT 4, Pancrease MT 16, Protilase, Panase, Ku-Zyme HP, Cotazym-S, Creon 10, Creon 20, Ultrase MT 20, Protilase MT-16, Creon 5, Pancrease, Pancrease MT 10, Vio-Moore, Panokase, Ilozyme, Pancrease MT 20, Ultrase, Ultrase MT 12, Pancron D/R, Encron-10, Ultrase MT 18, Arco-Lase, Lipram, Pancrecarb MS-8, Pancrecarb MS-4, Lipram-UL 18, Lipram-CR20, Lipram-UL 12, Lipram-UL 20, Viokase 16, Pancreatil-UL 12, Pangestyme CN 10, Pangestyme CN 20, Pangestyme MT 16, Pangestyme UL 18, Pangestyme EC, Kutrase, Ku-Zyme, Lipram-CR, Plaretase, Viokase 8, Lipram-CR5, Lapase, Dygase, Pancrecarb MS-16, Pangestyme UL 20, Panocaps, Panocaps MT 16, Lipram-CR10, Palcaps 10, Lipram-PN10, Lipram-PN16, Lipram-PN20, Panokase 16

Synonyms: n.a.

What is Ultresa?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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