Drug search by name

Paclitaxel (Conventional) and Trastuzumab-dkst Intravenous

Determining the interaction of Paclitaxel (Conventional) and Trastuzumab-dkst Intravenous and the possibility of their joint administration.

Check result:

Paclitaxel (Conventional) <> Trastuzumab-dkst Intravenous

Relevance: 04.06.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using trastuzumab together with PACLitaxel may increase the effects of trastuzumab. Contact your doctor if you experience chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, swelling, rapid weight gain, cough or wheezing, white patches or sores inside your mouth or on your lips, or fever, chills, body aches, and flu symptoms. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Non-human studies have demonstrated that paclitaxel can significantly increase the serum levels and decrease the clearance of trastuzumab. The mechanism is unknown.

MANAGEMENT: Patients should be monitored closely for signs of trastuzumab toxicity (e.g., cardiotoxicity, bone marrow depression).

References

"Product Information. Herceptin (trastuzumab)." Genentech, South San Francisco, CA.

Paclitaxel (Conventional)

Generic Name: paclitaxel

Brand name: Onxol, Taxol

Synonyms: Paclitaxel, PACLitaxel (Conventional)

What is Paclitaxel (Conventional)?

Trastuzumab-dkst Intravenous

Generic Name: trastuzumab

Brand name: Herceptin, Kanjinti, Ogivri

Synonyms: Trastuzumab

What is Trastuzumab-dkst Intravenous?

+ Add a drug Remove all

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

The list of popular interactions