Pamidronate Disodium and Vicodin

• Generic Name: pamidronate
• Dosage Forms: n.a.
• Other Brand Names: Aredia

Used in conjunction with achievement and maintenance of adequate hydration for the treatment of moderate to severe hypercalcemia associated with malignant neoplasms, with or without bone metastases.

More conservative measures (e.g., hydration alone or combined with loop diuretics) generally used for treatment of mild or asymptomatic hypercalcemia. Corticosteroid therapy may be beneficial in hypercalcemia associated with hematological malignancies.

Consider retreatment in patients with recurrent or refractory disease.

Treatment of moderate to severe Paget’s disease of bone (osteitis deformans) in symptomatic patients with multiple bone involvement [polyostotic] and elevated concentrations of serum alkaline phosphatase and urinary hydroxyproline.

May prevent or slow progression of complications (e.g., deformities, arthritis, fractures, neurologic manifestations, spinal cord compression, heart failure) in patients with Paget’s disease of bone. May not reverse established complications (e.g., severe deformities, deafness).

Treatment in patients refractory to calcitonin or etidronate disodium.

Used as an adjunct to antineoplastic therapy for the treatment of osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma.

Decreases the incidence and delays the development of bone-related complications (e.g., fractures or spinal cord compression, bone deterioration requiring radiotherapy or orthopedic surgery), and reduces bone pain and the need for supplemental analgesic therapy.

• Generic Name: acetaminophen / hydrocodone
• Dosage Forms: tablet
• Other Brand Names: Hycet, Lorcet, Lortab 10/325, Lortab 5/325, Lortab 75/325, Lortab Elixir, Norco, Verdrocet, Vicodin, Xodol, Anexsia, Dolorex Forte, Liquicet, Lortab, Maxidone, Polygesic, Stagesic, Zamicet, Zydone, Zyfrel

Vicodin contains a combination of acetaminophen and hydrocodone. Hydrocodone is an opioid pain medication. An opioid is sometimes called a narcotic. Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone.

Vicodin tablets are used for the relief of moderate to moderately severe pain.

Vicodin may also be used for purposes not listed in this medication guide.