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Pancreatin and Phillips Milk of Magnesia

Determining the interaction of Pancreatin and Phillips Milk of Magnesia and the possibility of their joint administration.

Check result:
Pancreatin <> Phillips Milk of Magnesia
Relevance: 17.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using magnesium hydroxide together with pancreatin can decrease the effects of pancreatin. Magnesium hydroxide and pancreatin doses should be separated by at least one hour. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of some formulations of pancreatic enzymes, resulting in earlier release and destruction of enzymatic activity.

MANAGEMENT: The administration of antacids and enteric-coated pancreatic enzyme products should be separated by at least one hour.

References
  • "Multum Information Services, Inc. Expert Review Panel"
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Pancreatin

Generic Name: pancreatin

Brand name: Hi-Vegi-Lip, Pancreatin 4X, Donnazyme, Digipepsin, Pan-2400

Synonyms: n.a.

Phillips Milk of Magnesia

Generic Name: magnesium hydroxide

Brand name: Ex-Lax Milk of Magnesia, Milk of Magnesia, Pedia-Lax Chewable, Phillips Milk of Magnesia, Dulcolax Milk of Magnesia, Concentrated Phillips Milk of Magnesia

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle