Pancreatin and Ravicti Oral Liquid
Determining the interaction of Pancreatin and Ravicti Oral Liquid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Pancreatin may increase the blood levels and effects of glycerol phenylbutyrate. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Concomitant use of glycerol phenylbutyrate with pancreatic enzyme replacement therapies containing lipase may increase the amount of phenylbutyrate available for absorption as well as the amount of its active metabolite, phenylacetic acid (PAA), available in the circulation. Increased levels of PAA may increase the risk of adverse events such as neurotoxicity. However, clinical data are not available.
MANAGEMENT: Caution and close monitoring of ammonia levels is recommended if glycerol phenylbutyrate is to be administered with pancreatic enzyme replacement therapies containing lipase. The dose of glycerol phenylbutyrate should be adjusted as necessary per local guidelines.
- "Product Information. Ravicti (glycerol phenylbutyrate)." Hyperion Therapeutics Inc, South San Francisco, CA.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: pancreatin
Brand name: Hi-Vegi-Lip, Pancreatin 4X, Donnazyme, Digipepsin, Pan-2400
Synonyms: n.a.
Generic Name: glycerol phenylbutyrate
Brand name: Ravicti
Synonyms: Ravicti
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pancreatin-Rayaldee
- Pancreatin-Rayos
- Pancreatin-Razadyne
- Pancreatin-Razadyne (Galantamine Solution)
- Pancreatin-Razadyne (Galantamine Tablets)
- Pancreatin-Razadyne ER
- Ravicti Oral Liquid-Pancreatin 4X
- Ravicti Oral Liquid-Pancreatin Capsules and Tablets
- Ravicti Oral Liquid-Pancreaze
- Ravicti Oral Liquid-Pancrelipase
- Ravicti Oral Liquid-Pancrelipase Capsules
- Ravicti Oral Liquid-Pancrelipase Tablets