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Pancreatin and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Determining the interaction of Pancreatin and Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets) and the possibility of their joint administration.

Check result:
Pancreatin <> Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)
Relevance: 17.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sodium bicarbonate together with pancreatin can decrease the effects of pancreatin. Sodium bicarbonate and pancreatin doses should be separated by at least one hour. Contact your doctor if your condition worsens. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of some formulations of pancreatic enzymes, resulting in earlier release and destruction of enzymatic activity.

MANAGEMENT: The administration of antacids and enteric-coated pancreatic enzyme products should be separated by at least one hour.

References
  • "Multum Information Services, Inc. Expert Review Panel"
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Pancreatin

Generic Name: pancreatin

Brand name: Hi-Vegi-Lip, Pancreatin 4X, Donnazyme, Digipepsin, Pan-2400

Synonyms: n.a.

Zegerid (Omeprazole and Sodium Bicarbonate Powder Packets)

Generic Name: omeprazole / sodium bicarbonate

Brand name: Zegerid, Zegerid OTC

Synonyms: Zegerid

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.