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Pancreatin 4X and Precose

Determining the interaction of Pancreatin 4X and Precose and the possibility of their joint administration.

Check result:
Pancreatin 4X <> Precose
Relevance: 10.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pancreatin together with acarbose. Using these medications together can make acarbose less effective. You should contact your doctor if you experience loss of blood sugar control. You may need a dose adjustment and you may need to check your blood sugar more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: The effect of alpha-glucosidase inhibitors may be reduced when taken concomitantly with intestinal adsorbents (e.g., charcoal) or carbohydrate-splitting digestive enzymes (e.g., amylase, pancreatin).

MANAGEMENT: Alpha-glucosidase inhibitors should not be administered simultaneously with intestinal adsorbents or preparations containing carbohydrate-splitting digestive enzymes. The optimal dosing interval between these agents has not been established. Postprandial blood glucose and glycosylated hemoglobin (HbA1c) should be monitored to ensure adequate therapeutic response to alpha-glucosidase inhibitor therapy.

References
  • "Product Information. Precose (acarbose)." Bayer, West Haven, CT.
  • "Product Information. Glyset (miglitol)." Bayer, West Haven, CT.
Pancreatin 4X

Generic Name: pancreatin

Brand name: Hi-Vegi-Lip, Pancreatin 4X, Pan-2400, Donnazyme, Digipepsin

Synonyms: n.a.

Precose

Generic Name: acarbose

Brand name: Precose

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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Disease interaction