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Pancuronium and Qualaquin

Determining the interaction of Pancuronium and Qualaquin and the possibility of their joint administration.

Check result:
Pancuronium <> Qualaquin
Relevance: 24.09.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using pancuronium together with quiNINE can increase the effects of pancuronium. You should be closely monitored for prolong breathing cessation and respiratory paralysis after use of quiNINE. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Quinine may enhance the effects of neuromuscular blockers. Dyspnea and recurarisation have been reported in a patient who received gentamicin and penicillin before surgery, succinylcholine and pancuronium intraoperatively, and intravenous quinine after reversal of neuromuscular blockade. The mechanism is not unknown; however, the neuromuscular blocking effects of gentamicin may have also been involved.

MANAGEMENT: Patients should be closely monitored for prolonged or excessive neuromuscular blockade and treated appropriately.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Pancuronium

Generic Name: pancuronium

Brand name:

Synonyms: n.a.

Qualaquin

Generic Name: quinine

Brand name: Qualaquin, QM-260, Quinamm

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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