Pancuronium Bromide and Vancomycin Oral Solution
Determining the interaction of Pancuronium Bromide and Vancomycin Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using pancuronium together with vancomycin can prolong the effects of pancuronium. You should be closely monitored for prolong breathing cessation and respiratory paralysis after use of vancomycin. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Like other polypeptide antibiotics, vancomycin may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular potassium or decreased ionized serum calcium.
MANAGEMENT: Patients should be monitored for excessive and prolonged neuromuscular blockade.
- Kronenfeld MA, Thomas SJ, Turndorf H "Recurrence of neuromuscular blockade after reversal of vecuronium in a patient receiving polymyxin/amikacin sternal irrigation." Anesthesiology 65 (1986): 93-4
- Huang KC, Heise A, Shrader AK, Tsueda K "Vancomycin enhances the neuromuscular blockade of vecuronium." Anesth Analg 71 (1990): 194-6
Generic Name: pancuronium
Brand name:
Synonyms: Pancuronium
Generic Name: vancomycin
Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50
Synonyms: Vancomycin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pancuronium Bromide-Vandazole
- Pancuronium Bromide-Vandetanib
- Pancuronium Bromide-Vanos
- Pancuronium Bromide-Vanoxide-HC
- Pancuronium Bromide-Vanquish
- Pancuronium Bromide-Vanspar
- Vancomycin Oral Solution-Pandel
- Vancomycin Oral Solution-Pandel Topical application
- Vancomycin Oral Solution-Pangestyme EC
- Vancomycin Oral Solution-Panhematin
- Vancomycin Oral Solution-Panitumumab
- Vancomycin Oral Solution-Panitumumab Intravenous