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Panlor Tablet and Rilutek

Determining the interaction of Panlor Tablet and Rilutek and the possibility of their joint administration.

Check result:
Panlor Tablet <> Rilutek
Relevance: 13.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Caffeine may increase the serum concentration of riluzole. Riluzole is metabolized by the CYP450 1A2 isoenzyme. Caffeine inhibits this particular isoenzyme. The clinical significance of this interaction is not known. The patient should be closely monitored for altered clinical effect.

References
  • "Product Information. Rilutek (riluzole)." Rhone-Poulenc Rorer, Collegeville, PA.
Panlor Tablet

Generic Name: acetaminophen / caffeine / dihydrocodeine

Brand name: Dvorah, Panlor Tablet, Trezix, Panlor DC, Panlor SS, Zerlor

Synonyms: Panlor Tablets

Rilutek

Generic Name: riluzole

Brand name: Rilutek, Tiglutik

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction