Pantoprazole Sodium and Zoledronic Acid Injection Concentrate

• Generic Name: pantoprazole
• Dosage Forms: n.a.
• Other Brand Names: Protonix, Protonix IV

Orally for short-term treatment of erosive esophagitis in patients with GERD.

Orally to maintain healing and decrease recurrence of erosive esophagitis.

IV for up to 7–10 days in the treatment of GERD in patients with a history of erosive esophagitis. Discontinue IV therapy as soon as patient is able to initiate or resume oral therapy with the drug.

Orally for long-term treatment of pathologic hypersecretory conditions, including Zollinger-Ellison syndrome.

IV for up to 6 days in the treatment of pathologic hypersecretory conditions associated with Zollinger-Ellison syndrome or other neoplastic conditions.

Orally for treatment of duodenal ulcer.

Orally for treatment of gastric ulcer.

Some evidence for use of proton-pump inhibitors (e.g., omeprazole) for gastric acid suppressive therapy as an adjunct in the management of upper GI Crohn’s disease, including esophageal, gastroduodenal, and jejunoileal disease.

• Generic Name: zoledronic acid
• Dosage Forms: injection, solution, concentrate
• Other Brand Names: Reclast, Zometa, Zometa Concentrate, Aclasta

Zoledronic acid (sometimes called zoledronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Reclast and Zometa are two different brands of zoledronic acid.

Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. zoledronic acid is for use when you have a high risk of bone fracture due to osteoporosis. Reclast is also used to treat Paget's disease of bone.

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

You should not use Reclast and Zometa at the same time.

Zoledronic acid may also be used for purposes not listed in this medication guide.