Pasireotide Extended-Release Injection and Phentermine Hydrochloride

• Generic Name: pasireotide
• Dosage Forms: n.a.
• Other Brand Names: Signifor, Signifor LAR

• It is used to treat Cushing's disease.
• It is used to treat acromegaly.

• Generic Name: phentermine
• Dosage Forms: n.a.
• Other Brand Names: Adipex-P, Lomaira, Suprenza

Adjunct to exercise, behavioral modification, and caloric restriction in the short-term management (a few weeks) of exogenous obesity.

May use in patients with no underlying risk factor but a pretreatment body mass index (BMI) of ≥30 kg/m2 and in those with an underlying risk factor (e.g., hypertension, diabetes mellitus, hyperlipidemia) and a pretreatment BMI of ≥27 kg/m2.

Use only for short-term monotherapy; not for use in combination with any other drug for weight loss, including SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline) or MAO inhibitors. (See Warnings under Cautions.)