Paxil and Ropivacaine Hydrochloride

• Generic Name: paroxetine
• Dosage Forms: tablet
• Other Brand Names: Paxil, Brisdelle, Paxil CR, Pexeva

Paxil (paroxetine) is an antidepressant that belongs to group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders.

Paxil is used to treat depression, including major depressive disorder.

Paxil is also used to treat panic disorder, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

• Generic Name: ropivacaine
• Dosage Forms: n.a.
• Other Brand Names: Naropin, Naropin Polyamp, Naropin SDV, Naropin Novaplus

Local or regional anesthesia for surgery (including cesarean section) and management of acute pain (e.g., postoperative pain, labor pain).

Used as a component of multimodal analgesia (i.e., simultaneous use of a combination of analgesic drugs and techniques that target different mechanisms) in the management of postoperative pain.

Compared with bupivacaine, generally has a similar onset and duration of sensory block, but a lower intensity and shorter duration of motor block. Appears to have a lower potential for CNS and cardiovascular toxicity than bupivacaine.

Not recommended for obstetrical paracervical block, retrobulbar block for ophthalmic surgery, spinal anesthesia (subarachnoid block), or IV regional anesthesia (Bier block) because of lack of clinical experience and/or risk of toxicity.