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PCE Dispertab and Viramune Suspension

Determining the interaction of PCE Dispertab and Viramune Suspension and the possibility of their joint administration.

Check result:

PCE Dispertab <> Viramune Suspension

Relevance: 03.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this interaction is not currently available.MONITOR: Coadministration with nevirapine may decrease the plasma concentrations and therapeutic efficacy of drugs that are substrates of CYP450 3A4. The proposed mechanism is increased clearance due to nevirapine-mediated induction of CYP450 3A4. MANAGEMENT: Caution is advised if nevirapine is used concomitantly with drugs that are CYP450 3A4 substrates. Dosage adjustments as well as clinical and laboratory monitoring of coadministered drugs should be considered whenever nevirapine is added to or withdrawn from therapy. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Viramune XR (nevirapine)." Boehringer Ingelheim, Ridgefield, CT. Cerner Multum, Inc. "Australian Product Information." O 0 "Product Information. Viramune (nevirapine)." Boehringer-Ingelheim, Ridgefield, CT. View all 4 references

Professional:

MONITOR: Coadministration with nevirapine may decrease the plasma concentrations and therapeutic efficacy of drugs that are substrates of CYP450 3A4. The proposed mechanism is increased clearance due to nevirapine-mediated induction of CYP450 3A4.

MANAGEMENT: Caution is advised if nevirapine is used concomitantly with drugs that are CYP450 3A4 substrates. Dosage adjustments as well as clinical and laboratory monitoring of coadministered drugs should be considered whenever nevirapine is added to or withdrawn from therapy.

References

Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
"Product Information. Viramune XR (nevirapine)." Boehringer Ingelheim, Ridgefield, CT.
Cerner Multum, Inc. "Australian Product Information." O 0
"Product Information. Viramune (nevirapine)." Boehringer-Ingelheim, Ridgefield, CT.

PCE Dispertab

Generic Name: erythromycin

Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV

Synonyms: PCE Dispertab (Oral), PCE, PCE (Oral)

What is PCE Dispertab?

Viramune Suspension

Generic Name: nevirapine

Brand name: Viramune, Viramune XR

Synonyms: Viramune

What is Viramune Suspension?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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