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Pediazole and Phenelzine

Determining the interaction of Pediazole and Phenelzine and the possibility of their joint administration.

Check result:
Pediazole <> Phenelzine
Relevance: 16.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sulfiSOXAZOLE together with phenelzine can increase the blood levels or add to the side effects of either medication. Contact your doctor if you experience muscle pain, and numbness,tingling, burning, and prickling in the extremities. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: One case report has described a possible interaction between sulfisoxazole and phenelzine, resulting in neurologic symptoms, muscle pain, and paresthesias. The mechanism is unknown and causality is unclear.

MANAGEMENT: The patient should be monitored for toxicity from either drug.

References
  • Boyer W, Lake C "Interaction of phenelzine and sulfisoxazole." Am J Psychiatry 140 (1983): 264-5
Pediazole

Generic Name: erythromycin / sulfisoxazole

Brand name:

Synonyms: Pediazole (Oral)

Phenelzine

Generic Name: phenelzine

Brand name: Nardil

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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