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Pediazole and Potaba

Determining the interaction of Pediazole and Potaba and the possibility of their joint administration.

Check result:
Pediazole <> Potaba
Relevance: 16.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using sulfiSOXAZOLE and potassium aminobenzoate is not recommended. Call your doctor if you notice that sulfiSOXAZOLE is not working or if your infection worsens. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Potassium aminobenzoate may inactivate antibacterial sulfonamides. Sulfonamides are structural analogues and competitive inhibitors of para-aminobenzoic acid, which is required by bacterial folic acid synthesis. Therefore, sufficient concentrations of potassium para-aminobenzoate may antagonize the antibacterial effects of sulfonamides.

MANAGEMENT: The manufacturer considers concomitant use contraindicated.

References
  • "Product Information. Potaba (potassium aminobenzoate)." Glenwood Inc, Englewood, NJ.
Pediazole

Generic Name: erythromycin / sulfisoxazole

Brand name:

Synonyms: Pediazole (Oral)

Potaba

Generic Name: potassium aminobenzoate

Brand name: Potaba

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction