Pegvaliase-pqpz Subcutaneous and Rosuvastatin Tablets

• Generic Name: pegvaliase
• Dosage Forms: n.a.
• Other Brand Names: Palynziq

Pegvaliase-pqpz injection is used to lower phenylalanine levels in the blood in adults with phenylketonuria (PKU), who have uncontrolled blood phenylalanine levels with their current treatment.

Pegvaliase-pqpz is available only under a restricted distribution program called Palynziq™ REMS (Risk Evaluation and Mitigation Strategy) Program.

• Generic Name: rosuvastatin
• Dosage Forms: tablet, film coated
• Other Brand Names: Crestor, Ezallor Sprinkle

Rosuvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Rosuvastatin is also used to treat hereditary types of high cholesterol (hypercholesterolemia): The heterozygous type (inherited from one parent) or the homozygous type (inherited from both parents).

For the heterozygous type, rosuvastatin can be used in children who are at least 8 years old. For the homozygous type, rosuvastatin can be used in children as young as 7 years old.

The Ezallor brand of rosuvastatin is for use only in adults.

Crestor is also used in adults to slow the progression of atherosclerosis (a build-up of plaque in blood vessels that can block blood flow).

Crestor is also used to lower the risk of stroke, heart attack, and other complications in men 50 years and older or women 60 years and older who have coronary heart disease or other risk factors.

Rosuvastatin may also be used for purposes not listed in this medication guide.